24/7 Space News
SPACE MEDICINE
Spinal implant allows Parkinson's patient to walk again
Spinal implant allows Parkinson's patient to walk again
By Alexandre Grosbois with Julien Dury in Paris
Lausanne (AFP) Nov 6, 2023

A man with advanced Parkinson's disease is now able to walk almost normally again thanks to electrodes implanted in his spinal cord, researchers said on Monday.

The medical first was achieved by Swiss researchers who had previously pioneered similar breakthroughs to help paraplegic people walk again.

"This could be a game-changing technology to help restore movement in people with advanced Parkinson's," said David Dexter, research director at Parkinson's UK, emphasising that the procedure is invasive and more research was needed.

Marc, the 62-year-old patient who lives in France, has suffered from the debilitating brain disorder for about 30 years.

Like more than 90 percent of people with advanced Parkinson's, Marc has had great difficulty walking.

What are known as "freezing" episodes -- during which patients are temporarily unable to move, putting them at risk of falling -- are particularly "awful", Marc told AFP.

"If you have an obstacle or if someone passes in front of you unexpectedly, you start to 'freeze' and you fall," said Marc, who asked not to reveal his last name.

Much remains unknown about Parkinson's disease, making treatment difficult. But the symptoms can seriously affect the lives of patients, sometimes confining them to bed or a wheelchair.

When the opportunity arose to undergo surgery in Switzerland, Marc leapt at the chance.

- 'I can go do whatever I want' -

"Now I can walk from one point to another without worrying about how I'm going to get there," he said.

"I can go for a walk, go out shopping by myself -- I can go do whatever I want."

The Swiss team, led by surgeon Jocelyne Bloch and neuroscientist Gregoire Courtine, implanted a complex system of electrodes called a "neuroprosthesis" at crucial points along Marc's spinal cord.

The pair had previously introduced the use of spinal cord implants to enable paraplegic patients to walk again.

The latest research, published in the journal Nature Medicine, works roughly along the same principle.

For Marc and other Parkinson's patients, communication between the brain and the spinal cord has been impaired by the progressive disappearance of neurons which generate the neurotransmitter dopamine.

Therefore, the neuroprosthesis has to not only send electrical stimulation to prompt walking, but also assume the role of the brain by properly timing the stimulation, so the resulting movements correspond to the patient's wishes.

"The idea is that we are going to measure residual movements -- so, the intention to walk -- with small sensors which are located in the legs," Courtine told AFP.

"Thanks to this, we know if the person wants to oscillate or stop, and we can adjust the stimulation accordingly," said Courtine, a researcher at the Swiss Federal Institute of Technology Lausanne.

- 'Major potential advance' -

The neuroprosthesis was first tested on primates, then implanted in Marc, who has used it for roughly eight hours a day over nearly two years.

Marc said he can now walk much more easily -- he is even planning a trip to Brazil -- but emphasised that it still requires concentration, particularly when climbing up stairs.

The Swiss team has expanded their experiment to a group of six Parkinson's patients, aiming to know how it could help others, given the disease affects people in different ways.

Treatment using the invasive implant could be quite expensive, potentially limiting how many patients would have access.

Bloch and Courtine have launched a startup called Onward looking at future marketing.

But even reaching this point represents "a major potential advance," Dexter said.

Related Links
Space Medicine Technology and Systems

Subscribe Free To Our Daily Newsletters
Tweet

RELATED CONTENT
The following news reports may link to other Space Media Network websites.
SPACE MEDICINE
High-tech helmet holds promise for deaf American football players
Washington (AFP) Nov 4, 2023
Coach Chuck Goldstein often finds himself jumping up and down on the sidelines of the field - trying, in vain, to get his players' attention. That's because all but one of the players on the Gallaudet University American football team, in Washington, are all deaf or hard of hearing. "If our player is not looking at us, they're not gonna know what we're telling them," Goldstein tells AFP. That's what makes the helmet Goldstein is holding in his hands so revolutionary: it is equipped with an ... read more

SPACE MEDICINE
SwRI's Dr. Alan Stern conducts space research during suborbital spaceflight aboard Virgin Galactic's VSS Unity

Apollo astronaut Thomas K. Mattingly dies aged 87

NASA astronauts Moghbeli and O'Hara embark on rare all-female spacewalk

Australian school students are experimenting with 'space veggies' in a NASA initiative

SPACE MEDICINE
SQX-2Y rocket demonstrates vertical take-off and landing capabilities

SpinLaunch announces new leadership roles

SpaceX launches 23 Starlink Internet satellites after aborted mission

Hot summer for Europe's reusable rocket engine

SPACE MEDICINE
Estimating depositional timing on Mars using cosmogenic radionuclide data

Mars Climate Sounder data reveals new cloud trends, study shows

Bewitched Battery: Sols 3994-3995

Scientists discover molten layer covering Martian core

SPACE MEDICINE
New scientific experimental samples from China's space station return to Earth

Shenzhou XVI crew return after 'very cool journey'

Chinese astronauts return to Earth with fruitful experimental results

Chinese astronauts return to Earth after 'successful' mission

SPACE MEDICINE
InSPA collaborates with multi-sector partners to fast-track space commercialization

New technologies for the future of European space

Follow NASA's Starling Swarm in Real Time

Fugro SpAARC's operations set to grow with new funding from Western Australian Govt

SPACE MEDICINE
'Call of Duty', the stalwart video game veteran, turns 20

NRL ISS Mission seeks new bioinspired materials

Panama bans new mining contracts in response to mass protests

NASA's InSPA Aims to Stimulate Commercial Manufacturing in Low Earth Orbit

SPACE MEDICINE
Scorching, seven-planet system revealed by new Kepler Exoplanet list

Jurassic worlds might be easier to spot than modern Earth

Giant planets cast a deadly pall

ET phone Dublin? Astrophysicists scan the Galaxy for signs of life

SPACE MEDICINE
Salts and organics observed on Ganymede's surface by June

New jet stream discovered in Jupiter's upper atmosphere

Uranus aurora discovery offers clues to habitable icy worlds

How NASA is protecting Europa Clipper from space radiation

Subscribe Free To Our Daily Newsletters




The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.