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ISRO developing microbe cultivation device for orbital biological experiments by Sushmita Panda New Delhi (Sputnik) Sep 07, 2021
According to state scientific representatives, India's space agency (ISRO) must identify indigenous solutions to achieve its ambitious space program. Researchers also state that the device has separate compartments that can conduct different kinds of experiments. Scientific representatives from one of India's premiere institutes, the Indian Institute of Science (IISc), partnering with the country's space agency, Indian Space Research Organisation (ISRO), have reportedly developed a device to cultivate microorganisms in space, a move that could help researchers conduct biological experiments in orbit. A team of scientists led by Aloke Kumar, an associate professor in the Department of Mechanical Engineering, IIScs, showed in a study how the device can be used to activate and track the growth of a bacterium, Sporosarcina pasteurii, over several days, with little human involvement. The device uses an LED and photodiode sensor combination to track the growth of the bacterium by measuring the optical density, or scattering of light. During their experiment, the team made sure that the device was leak-proof and its orientation remained unaffected. "Now that we know this proof-of-concept works, we have already embarked on the next step ? getting a flight model [of the device] ready," said Koushik Viswanathan, an assistant professor in the Department of Mechanical Engineering, IISc, and a senior author of the study. According to researchers, the device can also be adapted to study more complex organisms, like worms, and could also be used for non-biological experiments. The study will be published in the November edition of the Acta Astronautica journal. Source: RIA Novosti
Mini CRISPR system promises easier cell engineering, gene therapy Washington DC (UPI) Sep 3, 2021 Scientists have developed a more compact CRISPR system that can be more easily delivered to cells. The technology, described Friday in the journal Molecular Cell, promises to make cell-engineering more effective and efficient. The world's most popular and powerful gene-editing tool, CRISPR-Cas9, has enabled numerous scientific discoveries. It works by excising specific DNA sequences using a gene-cutting protein, Cas9, sourced from bacterial immune systems. Because CRISPR-Cas9 and ... read more
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