Discovering New Molecules for Military Applications

The efficient discovery and production of new molecules is essential for a range of military capabilities-from developing safe chemical warfare agent simulants and medicines to counter emerging threats, to coatings, dyes, and specialty fuels for advanced performance.

Current approaches to develop molecules for specific applications, however, are intuition-driven, mired in slow iterative design and test cycles, and ultimately limited by the specific molecular expertise of the chemist who has to test each candidate molecule by hand.

Last week DARPA announced the Accelerated Molecular Discovery (AMD) program, which aims to develop new, AI-based systematic approaches that increase the pace of discovery and optimization of high-performance molecules. A Proposers Day webinar describing the goals of the program is scheduled for Oct.18, 2018.

"The ultimate goal of AMD is to speed the time to design, validate, and optimize new molecules with defined properties from several years to a few months, or even several weeks," said Anne Fischer, program manager in DARPA's Defense Sciences Office. "We aim to develop the AI tools, models and experimental systems to enable autonomous design of molecules to quickly meet DoD needs."

The program calls for teams of researchers to develop AI-based, closed-loop systems that automatically extract existing chemistry data from databases and text, perform autonomous experimental measurement and optimization, and use computational approaches to develop physics-based representations and predictive tools.

AMD performers will develop tools, models, and experimental capabilities to rapidly design, validate, and optimize molecules. Government partners will evaluate performer developments and test their ability to identify new molecules with specific combinations of functional properties that may be relevant to specific DoD application requirements.

"There are currently around 140 million known molecules, but the space of potential molecules is vastly larger than that, upwards of 1060," Fischer said.

"In DARPA's Make-It program, we've developed advanced ways to efficiently synthesize known molecules. AMD is taking the next step, where we will rapidly be able to explore the unknown molecular universe to design and produce completely new molecules with specific desired functions."

The AMD program seeks expertise in chemistry and chemical engineering, computer science, AI/machine learning, and mathematics. A Broad Agency Announcement (BAA) solicitation with full details is expected to be published soon on FedBizOpps here.

Related Links
DARPA's Make-It program
Space Technology News - Applications and Research

Tweet

Thanks for being there;
We need your help. The SpaceDaily news network continues to grow but revenues have never been harder to maintain.

With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords.

Our news coverage takes time and effort to publish 365 days a year.

If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.

SpaceDaily Monthly Supporter
$5+ Billed Monthly

paypal only

SpaceDaily Contributor
$5 Billed Once

credit card or paypal

Spheres can make concrete leaner, greener
Houston TX (SPX) Oct 09, 2018
Rice University scientists have developed micron-sized calcium silicate spheres that could lead to stronger and greener concrete, the world's most-used synthetic material. To Rice materials scientist Rouzbeh Shahsavari and graduate student Sung Hoon Hwang, the spheres represent building blocks that can be made at low cost and promise to mitigate the energy-intensive techniques now used to make cement, the most common binder in concrete. The researchers formed the spheres in a solution around ... read more